姓名: 王璐
学科: 遗传学
职称/人才类别: 副研究员
电话：0871-65033362
电子邮件: wanglu@ynu.edu.cn
个人简历：
2000年9月-2004年7月：山东大学，生命科学学院，理学学士
2004年9月-2010年12月：中科院上海植物生理生态研究所，国家基因研究中心，硕博连读，获博士学位，导师韩斌。
2011年3月-2017年12月：云南大学/云南生物资源保护与利用国家重点实验室，动物遗传多样性与进化团队，助理研究员。
2017年5月:入选云南大学“东陆中青年骨干教师培养计划”。
2017年12月至今：云南大学/云南生物资源保护与利用国家重点实验室，动物遗传多样性与进化团队，副研究员。
个人简介：
主持国家自然科学基金项目两项，参与多项，作为骨干参与973计划一项，负责横向项目2项。协助张亚平院士指导研究生已毕业2名硕士研究生，在读1名博士研究生及4名硕士研究生。招收遗传学专业以及生物工程专业（遗传方向）的学生。
主要研究方向
1）家犬驯化及复杂性状进化的遗传基础。
2）系统进化。
已发表期刊论文：
1. Yan-Hu Liu#, Lu Wang #, Tao Xu#, Xiaomin Guo, Yang Li, Ting-Ting Yin, He-Chuan Yang, Yang Hu, Adeniyi C. Adeola, Oscar J. Sanke, Newton O. Otecko, Meng Wang, Ya-Ping Ma, Olaogun S. Charles, Mikkel-Holger S. Sinding, Shyam Gopalakrishnan, José Alfredo Samaniego, Anders J. Hansen, Carlos Fernandes，Philippe Gaubert, Jane Budd, Philip M. Dawuda, Eli Knispel Rueness, Lubin Jiang, Weiwei Zhai, M.T.P Gilbert, Min-Sheng Peng, Xiaopeng Qi*, Guo-Dong Wang*, Ya-Ping Zhang*. 2017. Whole-genome sequencing of African dogs provides insights into adaptations against tropical parasites. Molecular Biology and Evolution online. (IF2017=6.202，生物I区)
2. Lu Wang #, Ya-Ping Ma#, Qi-Jun Zhou, Ya-Ping Zhang, Peter Savolainen, Guo-Dong Wang*. 2017. The geographical distribution of grey wolves (Canis lupus) in China: a systematic review. Zoological Research, 2016, 37(6): 315-326.
3. Hong Wu#, Yan-Hu Liu#, Guo-Dong Wang, Chun-Tao Yang, Newton O. Otecko, Fei Liu, Shi-Fang Wu, Lu Wang *, Li Yu*, Ya-Ping Zhang*. 2016. Identifying molecular signatures of hypoxia adaptation from sex chromosomes: a case for Tibetan Mastiff based on analyses of X chromosome. Scientific Reports 6:35004. (IF2016=5.228)
4. Li Yu*#, Guo-Dong Wang#, Jue Ruan#, Yong-Bin Chen#, Cui-Ping Yang#, Xue Cao#, Hong Wu#, Yan-Hu Liu#, Zheng-Lin Du#, Xiao-Ping Wang#, Jing Yang#, Shao-Chen Cheng#, Li Zhong, Lu Wang, Xuan Wang, Jing-Yang Hu, Lu Fang, Bing Bai, Kai-Le Wang, Na Yuan, Shi-Fang Wu, Bao-Guo Li, Jin-Guo Zhang, Ye-Qin Yang, Cheng-Lin Zhang, Yong-Cheng Long, Hai-Shu Li, Jing-Yuan Yang, David M Irwin, Oliver A Ryder, Ying Li, Chung-I Wu*, Ya-Ping Zhang*. 2016. Genomic analysis of snub-nosed monkeys (Rhinopithecus) identifies genes and processes related to high-altitude adaptation. Nature Genetics 48(8):947-952. (IF2016=31.616)
5. Guo-Dong Wang#, Weiwei Zhai#, He-Chuan Yang#, Lu Wang#, Li Zhong, Yan-Hu Liu, Ruo-Xi Fan, Ting-Ting Yin, Chun-Ling Zhu, Andrei D Poyarkov, David M Irwin, Marjo K Hytönen, Hannes Lohi, Chung-I Wu, Peter Savolainen*, Ya-Ping Zhang*. 2016. Out of southern East Asia: the natural history of domestic dogs across the world. Cell Research 26(1):21-33. (IF2016=14.812)
6. Shaojun Liu*#, Jing Luo#, Jing Chai#, Li Ren#, Yi Zhou#, Feng Huang#, Xiaochuan Liu#, Yubao Chen, Chun Zhang, Min Tao, Bin Lu, Wei Zhou, Guoliang Lin, Chao Mai, Shuo Yuan, Jun Wang, Tao Li, Qinbo Qin, Hao Feng, Kaikun Luo, Jun Xiao, Huan Zhong, Rurong Zhao, Wei Duan, Zhenyan Song, Yanqin Wang, Jing Wang, Li Zhong, Lu Wang, Zhaoli Ding, Zhenglin Du, Xuemei Lu, Yun Gao, Robert W. Murphy, Yun Liu, Axel Meyer*, Ya-Ping Zhang*. 2016. Genomic incompatibilities in the diploid and tetraploid offspring of the goldfish × common carp cross. Proceedings of the National Academy of Sciences of the United States of America (PNAS) 113(5):1327-1332. (IF2016= 9.423)
7. 柳延虎，王璐*，于黎*。2015。单分子实时测序技术的原理与应用。遗传 36(3):259-268. 【Yanhu Liu, Lu Wang*, Li Yu*. 2015. The principle and application of the single-molecule real-time sequencing technology. Hereditas 36(3):259-268.】
8. Bing Bai#, Wen-Ming Zhao#, Bi-Xia Tang#, Yan-Qing Wang, Lu Wang, Zhang Zhang, He-Chuan Yang, Yan-Hu Liu, Jun-Wei Zhu, David M. Irwin, Guo-Dong Wang*, Ya-Ping Zhang*. 2015. DoGSD: the dog and wolf genome SNP database. Nucleic Acids Research 43(Database issue):D777-D783. (IF2015=9.112)
9. Ming-Shan Wang#, Yan Li#, Min-Sheng Peng#, Li Zhong#, Zong-Ji Wang, Qi-Ye Li, Xiao-Long Tu, Yang Dong, Chun-Ling Zhu, Lu Wang, Min-Min Yang, Shi-Fang Wu, Yong-Wang Miao, Jian-Ping Liu, David M. Irwin, Wen Wang, Dong-Dong Wu*, Ya-Ping Zhang*. 2015. Genomic analyses reveal potential independent adaptation to high altitude in Tibetan chicken. Molecular Biology and Evolution 32(7):1880-1889. (IF2015=9.105)
10. 尹婷婷，王璐，王国栋*。2015。传染性肿瘤研究进展。遗传 37(11):1086-1094.【Tingting Yin, Lu Wang, Guodong Wang*. 2015. Recent advances in transmissible tumors. Hereditas 37(11):1086-1094.】
11. Zhong-Yin Zhou, Aimin Li, Li-Gang Wang, David M Irwin, Yan-Hu Liu, Dan Xu, Xu-Man Han, Lu Wang, Shi-Fang Wu, Li-Xian Wang*, Hai-Bing Xie*, Ya-Ping Zhang*. 2015. DNA methylation signatures of long intergenic noncoding RNAs in porcine adipose and muscle tissues. Scientific Reports 5:15435. (IF2015=5.578)
12. Dong-Dong Wu#, Ling-Qun Ye#, Yan Li#, Yan-Bo Sun, Yi Shao, Chunyan Chen, Zhu Zhu, Li Zhong, Lu Wang, David M. Irwin, Yong E. Zhang, Ya-Ping Zhang*. 2015. Integrative analyses of RNA editing, alternative splicing, and expression of young genes in human brain transcriptome by deep RNA sequencing. Journal of Molecular Cell Biology 7(4):314-325. (IF2015=6.771)
13. Yan-Bo Sun#, Zi-Jun Xiong#, Xue-Yan Xiang#, Shi-Ping Liu, Wei-Wei Zhou, Xiao-Long Tu, Li Zhong, Lu Wang, Dong-Dong Wu, Bao-Lin Zhang, Chun-Ling Zhu, Min-Min Yang, Hong-Man Chen, Fang Li, Long Zhou, Shao-Hong Feng, Chao Huang, Guo-Jie Zhang, David Irwin, David M. Hillis*, Robert W. Murphy, Huan-Ming Yang, Jing Che*, Jun Wang*, Ya-Ping Zhang*. 2015. Whole-genome sequence of the Tibetan frog Nanorana parkeri and the comparative evolution of tetrapod genomes. Proceedings of the National Academy of Sciences of the United States of America (PNAS) 112(11):E1257-E1262. (IF2015=9.674)
14. Guo-Dong Wang#, Ruo-Xi Fan#, Weiwei Zhai，Fei Liu, Lu Wang, Li Zhong, Hong Wu, He-Chuan Yang, Shi-Fang Wu, Chun-Ling Zhu, Yan Li, Yun Gao, Ri-Li Ge, Chung-I Wu, Ya-Ping Zhang*. 2014. Genetic Convergence in the Adaptation of Dogs and Humans to the High-Altitude Environment of the Tibetan Plateau. Genome Biology Evolution 6(8):2122-2128. (IF2014=4.532)
15. Xue Cao, David M. Irwin, Yan-Hu Liu, Lu-Guang Cheng, Lu Wang, Guo-Dong Wang*, Ya-Ping Zhang*. 2014. Balancing Selection on CDH2 May Be Related to the Behavioral Features of the Belgian Malinois. PLoS ONE 9(10):e110075. (IF2014=3.534)
16. Guo-dong Wang#, Weiwei Zhai#, He-chuan Yang, Ruo-xi Fan, Xue Cao, Li Zhong, Lu Wang, Fei Liu, Hong Wu, Lu-guang Cheng, Andrei D. Poyarkov, Nikolai A. Poyarkov JR, Shu-sheng Tang, Wen-ming Zhao, Yun Gao, Xue-mei Lv, David M. Irwin, Peter Savolainen, Chung-I Wu*, Ya-ping Zhang*. 2013. The genomics of selection in dogs and the parallel evolution between dogs and humans. Nature Communication 4:1860. (IF2013=10.015)
17. Guo Zong, Ahong Wang, Lu Wang, Guohua Liang, Minghong Gu, Tao Sang, Bin Han*. 2012. A Pyramid Breeding of Eight Grain-yield Related Quantitative Trait Loci Based on Marker-assistant and Phenotype Selection in Rice (Oryza sativa L.). Journal of Genetics and Genomics 39(7):335-350. (IF2012=1.883)
18. Lu Wang#, Ahong Wang#, Xuehui Huang, Qiang Zhao, Guojun Dong, Qian Qian, Tao Sang, Bin Han*. 2011. Mapping 49 quantitative trait loci at high resolution through sequencing-based genotyping of rice recombinant inbred lines. Theoretical and Applied Genetics 122(2):327-340. (IF2017=4.132)
19. Xuehui Huang#, Xinghua Wei#, Tao Sang#, Qiang Zhao#, Qi Feng#, Yan Zhao, Canyang Li, Chuanrang Zhu, Tingting Lu, Zhiwu Zhang, Meng Li, Danlin Fan, Yunli Guo, Ahong Wang, Lu Wang, Liuwei Deng, Wenjun Li, Yiqi Lu, Qijun Weng, Kunyan Liu, Tao Huang, Taoying Zhou, Yufeng Jing, Wei Li, Zhang Lin, Edward S Buckler, Qian Qian, Qi-Fa Zhang, Jiayang Li, Bin Han*. 2010. Genome-wide association studies of 14 agronomic traits in rice landraces. Nature Genetics 42(11):961-967. (IF2017=27.959)
20. Xuehui Huang#, Qi Feng#, Qian Qian#, Qiang Zhao#, Lu Wang#, Ahong Wang#, Jianping Guan, Danlin Fan, Qijun Weng, Tao Huang, Guojun Dong, Tao Sang, Bin Han*. 2009. High-throughput genotyping by whole-genome resequencing. Genome Research 19(6):1068-1076. (IF2017=11.992)
主持科研项目：
1. 国家自然科学基金，地区项目；基于系统发育基因组学方法构建果蝇科主干类群进化关系（31760617；39万（直接经费）；2018.1-2021.12；主持
2. 国家自然科学基金，青年项目；家犬驯化中与攻击性行为相关的人工选择研究（31201712）；23万；2013.1-2015.12；主持
3. 国家重点基础研究计划（973计划），子课题；家犬性状进化的遗传和基因组基础（013CB835202）；296万（到云南大学96万）；2013.01-2017.08；参与单位负责人4. 大麻种质基因组重测序，云南省农科院，18万，2014.10-2015.10；主持
5. Illumina高通量测序与分析，东莞博奥木华基因科技有限公司，49.22万，2015.07-2018.07；主要负责人
获奖及人才：
1. 2017.5，入选云南大学东陆中青年骨干教师培养计划
2. 2017.1，中国精品科技期刊顶尖学术论文“F5000”， 中国科学技术信息研究所，排名二
3. 2016.11，《遗传》2015年度优秀论文，《遗传》编辑部，排名二
